ICH Q6B requires, and Eurosequence offers:

• Amino Acid Analysis (AAA)
• N-terminal sequence analysis
• C-terminal sequence analysis
• Molecular Weight  Information
• Peptide mapping by LC or LC-MS
• S-S bridges analysis
• Molar extinction coefficient determination
• Post-translational modifications
• Impurity profiling by LC (SEC, RP, IEC)
• Aggregation analysis by SEC-HPLC
• Product related impurities analysis
• SDS-PAGE

Click here for full text Emea ICH Q6B document (.pdf)